Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin ...PyridoxinehydrochlorideProductingredientforPyridoxineShowfullentryforPyridoxineNamePyridoxinehydrochlorideDrugEntryPyridoxinePyridoxineisthe4-methanolformofvitaminB6,animportantwater-solublevitaminthatisnaturallypresentinmanyfoods.Asitsclassificationasavitaminimplies,VitaminB6(andpyridoxine)areessentialnutrientsrequiredfornormalfunctioningofmanybiologicalsystemswithinthebody.Whilemanyplantsandmicroorganismsareabletosynthesizepyridoxinethroughendogenousbiologicalprocesses,animalsmustobtainitthroughtheirdiet.Morespecifically,pyridoxineisconvertedtopyridoxal5-phosphateinthebody,whichisanimportantcoenzymeforsynthesisofaminoacids,neurotransmitters(serotonin,norepinephrine),sphingolipids,andaminolevulinicacid.It'simportanttonotethatVitaminB6isthecollectivetermforagroupofthreerelatedcompounds,pyridoxine,pyridoxal,andpyridoxamine,andtheirphosphorylatedderivatives,pyridoxine5'-phosphate,pyridoxal5'-phosphateandpyridoxamine5'-phosphate.AlthoughallsixofthesecompoundsshouldtechnicallybereferredtoasvitaminB6,thetermvitaminB6iscommonlyusedinterchangeablywithjustoneofthem,pyridoxine1.VitaminB6,principallyinitsbiologicallyactivecoenzymeformpyridoxal5'-phosphate,isinvolvedinawiderangeofbiochemicalreactions,includingthemetabolismofaminoacidsandglycogen,thesynthesisofnucleicacids,hemogloblin,sphingomyelinandothersphingolipids,andthesynthesisoftheneurotransmittersserotonin,dopamine,norepinephrineandgamma-aminobutyricacid(GABA)2.PyridoxineisusedmedicallyforthetreatmentofvitaminB6deficiencyandfortheprophylaxisofisoniazid-inducedperipheralneuropathy(duetoIsoniazid'smechanismofactionwhichcompetitivelyinhibitstheactionofpyridoxineintheabove-mentionedmetabolicfunctions).ItisalsousedincombinationwithDoxylamine(asthecommerciallyavailableproductDiclectin)forthetreatmentofnauseaandvomitinginpregnancy.SeefullentryforPyridoxineAccessionN