Diallyl disulfide (DADS) is an organosulfur compound derived from allicin, a natural compound found in garlic and related plants.

Diallyl disulfide (DADS) is a volatile organosulfur compound derived from garlic (Allium sativum L.), and it is known as an allelochemical ...ArticlesRichardSayreNewMexicoConsortium,UnitedStatesGolamJalalAhammedHenanUniversityofScienceandTechnology,ChinaHaoPengDepartmentofPlantPathology,CollegeofAgricultural,Human,andNaturalResourceSciences,WashingtonStateUniversity,UnitedStatesTheeditorandreviewers'affiliationsarethelatestprovidedontheirLoopresearchprofilesandmaynotreflecttheirsituationatthetimeofreview.AbstractIntroductionMaterialsandMethodsResultsDiscussionConclusionAuthorContributionsConflictofInterestStatementAcknowledgmentsSupplementaryMaterialAbbreviationsReferencesSuggestaResearchTopic>DownloadArticleDownloadPDFReadCubeEPUBXML(NLM)SupplementaryMaterialExportcitationEndNoteReferenceManagerSimpleTEXTfileBibTextotalviewsViewArticleImpactSuggestaResearchTopic>SHAREONOpenSupplementalDataORIGINALRESEARCHarticleFront.PlantSci.,09August2016|https://doi.org/10.3389/fpls.2016.01199TheGarlicAllelochemicalDiallylDisulfideAffectsTomatoRootGrowthbyInfluencingCellDivision,PhytohormoneBalanceandExpansinGeneExpressionFangCheng,ZhihuiCheng*,HuanwenMengandXiangweiTangDepartmentofVegetableScience,CollegeofHorticulture,NorthwestA&FUniversity,Yangling,ChinaDiallyldisulfide(DADS)isavolatileorganosulfurcompoundderivedfromgarlic(AlliumsativumL.),anditisknownasanallelochemicalresponsibleforthestrongallelopathicpotentialofgarlic.TheanticancerpropertiesofDADShavebeenstudiedinexperimentalanimalsandvarioustypesofcancercells,buttodate,littleisknownaboutitsmodeofactionasanallelochemicalatthecytologicallevel.ThecurrentresearchpresentsfurtherstudiesontheeffectsofDADSontomato(SolanumlycopersicumL.)seedgermination,rootgrowth,mitoticindex,andcellsizeinrootmeristem,aswellasthephytohormonelevelsandexpressionprofileofauxinbiosynthesisgenes(FZYs),auxintransportgenes(SlPINs),andexpansingenes(EXPs)intomatoroot.Theresultsshowedabiphasic,dose-dependenteffectontomatoseedgerminationandrootgrowthunderdiff

Diallyl disulfide (DADS) is a major organosulphur compound present in garlic with an anti-mitotic potential against colon neoplasic lesions in vivo and ...SkiptoMainContentAdvertisementSearchMenuAccountMenuMenuSignInRegisterNavbarSearchFilterThisissueAllCarcinogenesisAllJournalsMobileMicrositeSearchTermSearchSignInRegisterIssuesMoreContentAdvancearticlesEditor'sChoiceSubmitAuthorGuidelinesSubmissionSiteOpenAccessPurchaseAlertsAboutAboutCarcinogenesisEditorialBoardAdvertisingandCorporateServicesJournalsCareerNetworkSelf-ArchivingPolicyDispatchDatesIssuesMoreContentAdvancearticlesEditor'sChoiceSubmitAuthorGuidelinesSubmissionSiteOpenAccessPurchaseAlertsAboutAboutCarcinogenesisEditorialBoardAdvertisingandCorporateServicesJournalsCareerNetworkSelf-ArchivingPolicyDispatchDatesClosesearchfilterThisissueAllCarcinogenesisAllJournalssearchinputSearchAdvancedSearchSearchMenuArticleNavigationClosemobilesearchnavigationArticleNavigationVolume22Issue8August2001ArticleContentsAbstractIntroductionMaterialsandmethodsResultsDiscussionReferencesArticleNavigationEffectsofthegarliccompounddiallyldisulfideonthemetabolism,adherenceandcellcycleofHT-29coloncarcinomacells:evidenceofsensitiveandresistantsub-populationsVéroniqueRobert,VéroniqueRobertSearchforotherworksbythisauthoron:OxfordAcademicPubMedGoogleScholarBéatriceMouillé,BéatriceMouilléSearchforotherworksbythisauthoron:OxfordAcademicPubMedGoogleScholarCamilleMayeur,CamilleMayeurSearchforotherworksbythisauthoron:OxfordAcademicPubMedGoogleScholarMarieMichaud,MarieMichaudSearchforotherworksbythisauthoron:OxfordAcademicPubMedGoogleScholarFrançoisBlachierFrançoisBlachierSearchforotherworksbythisauthoron:OxfordAcademicPubMedGoogleScholarCarcinogenesis,Volume22,Issue8,August2001,Pages1155–1161,https://doi.org/10.1093/carcin/22.8.1155Published:01August2001ArticlehistoryReceived:02February2001Revisionreceived:17April2001Accepted:18April2001Published:01August2001PDFSplitViewViewsArticlecontentsFigures&tablesVideoAudioSupplementa

Diallyl sulfide (DAS) and other organosulfur compounds are chief constituents of garlic. These compounds have many health benefits, as they are very ...NCBISkiptomaincontentSkiptonavigationResourcesHowToAboutNCBIAccesskeysMyNCBISignintoNCBISignOutTryoutPMCLabsandtelluswhatyouthink.LearnMore.JournalListHHSAuthorManuscriptsPMC4663692CurrDrugMetab.Authormanuscript;availableinPMC2015Nov30.Publishedinfinaleditedformas:CurrDrugMetab.2015;16(6):486–503.PMCID:PMC4663692NIHMSID:NIHMS736820PMID:26264202DiallylSulfide:PotentialUseinNovelTherapeuticInterventionsinAlcohol,Drugs,andDiseaseMediatedCellularToxicitybyTargetingCytochromeP4502E1PSSRao,1,ΠNarasimhaMMidde,1,ΠDuaneD.Miller,1SubhashChauhan,1AnilKumar,2andSantoshKumar1,*PSSRao1PharmaceuticalSciences,CollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,Memphis,TN38163FindarticlesbyPSSRaoNarasimhaMMidde1PharmaceuticalSciences,CollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,Memphis,TN38163FindarticlesbyNarasimhaMMiddeDuaneD.Miller1PharmaceuticalSciences,CollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,Memphis,TN38163FindarticlesbyDuaneD.MillerSubhashChauhan1PharmaceuticalSciences,CollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,Memphis,TN38163FindarticlesbySubhashChauhanAnilKumar2PharmacologyandToxicology,SchoolofPharmacy,UniversityofMissouri-KansasCity,KansasCity,MO64108FindarticlesbyAnilKumarSantoshKumar1PharmaceuticalSciences,CollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,Memphis,TN38163FindarticlesbySantoshKumarAuthorinformationCopyrightandLicenseinformationDisclaimer1PharmaceuticalSciences,CollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,Memphis,TN381632PharmacologyandToxicology,SchoolofPharmacy,UniversityofMissouri-KansasCity,KansasCity,MO64108*AddresscorrespondencetothisauthorattheCollegeofPharmacy,UniversityofTennesseeHealthScienceCenter,881MadisonAve,Rm456,Memphis,TN38163;Tel:901-448-7157;ude.cshtu@hsotnaskΠEqualcontributionsCopyrightnoticeThepublisher'sfinal

Diallyl disulfide (DADS) and allyl methyl sulfide (AMS) have been known as a metabolic product of sulfur-containing foods, typically garlic.SkiptomaincontentThankyouforvisitingnature.com.YouareusingabrowserversionwithlimitedsupportforCSS.Toobtainthebestexperience,werecommendyouuseamoreuptodatebrowser(orturnoffcompatibilitymodeinInternetExplorer).Inthemeantime,toensurecontinuedsupport,wearedisplayingthesitewithoutstylesandJavaScript.AdvertisementnaturescientificreportsarticlesarticleMeasurementofdiallyldisulfideandallylmethylsulfideemanatingfromhumanskinsurfaceandinfluenceofingestionofgrilledgarlicDownloadPDFSubjectsBioanalyticalchemistryDigestivesignsandsymptomsAbstractDiallyldisulfide(DADS)andallylmethylsulfide(AMS)havebeenknownasametabolicproductofsulfur-containingfoods,typicallygarlic.Theodourofsuchorganosulfurcompoundsfollowinggarlicingestionisoftenconsideredasanunpleasantelement.AlthoughpreviousstudieshaveidentifiedtheDADSandAMSassociatedwithgarlicbreath,nostudyhasbeenreportedonthedeterminationofbothcompoundsemanatingfromhumanskinsurface.ThisstudyaimedtodemonstratetheeffectofgarlicingestiononthedermalemissionsofDADSandAMSusingapassivefluxsamplercoupledwithgaschromatography-massspectrometry.Firstly,baselinelevelswereinvestigatedfor30healthyvolunteersintheirdailylife.Theresultsof1h-samplingattheforearmshowedtheemissionfluxesofbothcompoundsfollowedthelognormaldistributionwithageometricmeanof0.18 ng cm−2h−1forDADSand0.22 ng cm−2h−1forAMS.Subsequently,thegarlicingestiontestswereconductedforselectedvolunteers.TheemissionfluxofDADSincreasedjustaftergrilledgarlicingestionanddecreasedgraduallythereafter.Incontrast,thedermalemissionfluxofAMSreachedapeakat30 minafteringestion,andthengraduallydecreased.ThispeakshiftsuggestsAMSisrelativelylatentintheskinorgans.DownloadPDFIntroductionGarlic(Alliumsativum)isabulbthathasbeenusedasaspice,functionalfoodandtraditionalmedicineallaroundtheworldsinceancienttimes1,2.Ingestionofgarlicisknowntohavemanyhealthbenefits;ithelpsinloweringbl

Diallyl disulfide | C6H10S2 | CID 16590 - structure, chemical names, physical and chemical properties, classification, patents, literature, ...

Diallyl disulfide (DADS or 4,5-dithia-1,7-octadiene) is an organosulfur compound derived from garlic and a few other genus Allium plants.DiallyldisulfideFromWikipedia,thefreeencyclopediaJumptonavigationJumptosearchChemicalcompoundDiallyldisulfideNamesPreferredIUPACname3-[(Prop-2-en-1-yl)disulfanyl]prop-1-eneOthernamesDiallyldisulfideGarlicin1,2-Diallyldisulfane(notrecommended)4,5-Dithia-1,7-octadieneIdentifiersCASNumber2179-57-9 Y3Dmodel(JSmol)InteractiveimageBeilsteinReference1699241ChEBICHEBI:4488 YChEMBLChEMBL366603 YChemSpider15730 YECHAInfoCard100.016.862ECNumber218-548-6GmelinReference217847KEGGC08369 YPubChemCID16590UNII5HI47O6OA7 YCompToxDashboard(EPA)DTXSID9035206InChIInChI=1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2 YKey: PFRGXCVKLLPLIP-UHFFFAOYSA-N YInChI=1/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2Key: PFRGXCVKLLPLIP-UHFFFAOYAXSMILESS(SC\C=C)C\C=CPropertiesChemicalformulaC6H10S2Molarmass146.28g/molAppearanceyellowishclearliquidwithanintensegarlicsmell[1]Density1.01g/cm3[2]Boilingpoint180 °C(356 °F;453 K)Solubilityinwatersolubleinethanolandoils[1]HazardsGHSpictogramsGHSSignalwordDangerGHShazardstatementsH226,H301,H315,H317,H319GHSprecautionarystatementsP210,P233,P240,P241,P242,P243,P261,P264,P270,P272,P280,P301+310,P302+352,P303+361+353,P305+351+338,P321,P330,P332+313,P333+313,P337+313,P362,P363,P370+378,P403+235,P405Exceptwhereotherwisenoted,dataaregivenformaterialsintheirstandardstate(at25 °C[77 °F],100 kPa).Y verify (whatis YN ?)Infobox referencesChemicalcompoundDiallyldisulfide(DADSor4,5-dithia-1,7-octadiene)isanorganosulfurcompoundderivedfromgarlicandafewothergenusAlliumplants.[3]Alongwithdiallyltrisulfideanddiallyltetrasulfide,itisoneoftheprincipalcomponentsofthedistilledoilofgarlic.Itisayellowishliquidwhichisinsolubleinwaterandhasastronggarlicodor.Itisproducedduringthedecompositionofallicin,whichisreleaseduponcrushinggarlicandotherplantsofthefamilyAlliaceae.Diallyldisulfidehasmanyofthehealthbenefitsofgarlic,butitisalsoanallergencausinggarlicallergy.H